ea0056p166 | Bone ' Osteoporosis | ECE2018
Arai Hiroshi
, Kanai Yugo
, Nakamoto Yuji
, Nagai Hiroki
, Sakamori Yuichi
, Yasoda Akihiro
, Inagaki Nobuya
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by the abnormal production of fibroblast growth factor 23 (FGF23) in the tumor. Here we report a case of TIO with pulmonary adenocarcinoma. A 61-year old woman was referred to our hospital. She was suffering from severe polyarthralgia and bilateral limb weakness. Her blood chemistry revealed high alkaline phosphatase, low phosphate, low calcium, and low 1,25-(OH)2D3. Bone-scintigrap...